Rare human mitochondrial HV lineages spread from the Near East and Caucasus during post-LGM and Neolithic expansions.

ABSTRACT: Of particular significance to human population history in Eurasia are the migratory events that connected the Near East to Europe after the Last Glacial Maximum (LGM). Utilizing 315 HV*(xH,V) mitogenomes, including 27 contemporary lineages first reported here, we found the genetic signatures for distinctive movements out of the Near East and South Caucasus both westward into Europe and eastward into South Asia. The parallel phylogeographies of rare, yet widely distributed HV*(xH,V) subclades reveal a connection between the Italian Peninsula and South Caucasus, resulting from at least two (post-LGM, Neolithic) waves of migration. Many of these subclades originated in a population ancestral to contemporary Armenians and Assyrians. One such subclade, HV1b-152, supports a postexilic, northern

SUBMITTER: Shamoon-Pour M 

PROVIDER: S-EPMC6791841 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature