Finding New Cell Wall Regulatory Genes in Populus trichocarpa Using Multiple Lines of Evidence.

ABSTRACT: Understanding the regulatory network controlling cell wall biosynthesis is of great interest in Populus trichocarpa, both because of its status as a model woody perennial and its importance for lignocellulosic products. We searched for genes with putatively unknown roles in regulating cell wall biosynthesis using an extended network-based Lines of Evidence (LOE) pipeline to combine multiple omics data sets in P. trichocarpa, including gene coexpression, gene comethylation, population level pairwise SNP correlations, and two distinct SNP-metabolite Genome Wide Association Study (GWAS) layers. By incorporating validation, ranking, and filtering approaches we produced a list of nine high priority gene candidates for involvement in the regulation of cell wall biosynthesis. We sub

SUBMITTER: Furches A 

PROVIDER: S-EPMC6791931 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature