Perioperative characteristics and management of liver transplantation for isolated methylmalonic acidemia-the largest experience in China.

ABSTRACT:

Background

There are few detailed consensus and guidelines on perioperative clinical characteristics of liver transplantation (LT) in patients with methylmalonic acidemia (MMA). This retrospective study investigated details of the clinical course and individualized treatment plan of the center with largest experience in China.

Methods

A total of 7 MMA patients undergoing LT in Beijing Friendship Hospital from June 2013 to December 2017 were enrolled in the study, whose clinical data (clinical characteristics, laboratory findings, chronological changes in urine MMA levels, treatment, etc.) during perioperative period were analyzed retrospectively. All the patients received strict postoperative management.

Results

All the 7 cases were confirmed to have isolated MMA, amo

SUBMITTER: Jiang YZ 

PROVIDER: S-EPMC6791977 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature