The Association Between Hysterectomy and Ovarian Cancer Risk: A Population-Based Record-Linkage Study.

ABSTRACT:

Background

Recent studies have called into question the long-held belief that hysterectomy without oophorectomy protects against ovarian cancer. This population-based longitudinal record-linkage study aimed to explore this relationship, overall and by age at hysterectomy, time period, surgery type, and indication for hysterectomy.

Methods

We followed the female adult Western Australian population (837 942 women) across a 27-year period using linked electoral, hospital, births, deaths, and cancer records. Surgery dates were determined from hospital records, and ovarian cancer diagnoses (n = 1640) were ascertained from cancer registry records. We used Cox regression to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between hysterectomy and

SUBMITTER: Dixon-Suen SC 

PROVIDER: S-EPMC6792101 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature