Crosstalk between epigenetic silencing and infection by tobacco rattle virus in Arabidopsis.

ABSTRACT: DNA methylation is an important epigenetic mechanism for controlling innate immunity against microbial pathogens in plants. Little is known, however, about the manner in which viral infections interact with DNA methylation pathways. Here we investigate the crosstalk between epigenetic silencing and viral infections in Arabidopsis inflorescences. We found that tobacco rattle virus (TRV) causes changes in the expression of key transcriptional gene silencing factors with RNA-directed DNA methylation activities that coincide with changes in methylation at the whole genome level. Viral susceptibility/resistance was altered in DNA (de)methylation-deficient mutants, suggesting that DNA methylation is an important regulatory system controlling TRV proliferation. We further show that several transp

SUBMITTER: Diezma-Navas L 

PROVIDER: S-EPMC6792132 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature