Fatty acids, epigenetic mechanisms and chronic diseases: a systematic review.

ABSTRACT: BACKGROUND:Chronic illnesses like obesity, type 2 diabetes (T2D) and cardiovascular diseases, are worldwide major causes of morbidity and mortality. These pathological conditions involve interactions between environmental, genetic, and epigenetic factors. Recent advances in nutriepigenomics are contributing to clarify the role of some nutritional factors, including dietary fatty acids in gene expression regulation. This systematic review assesses currently available information concerning the role of the different fatty acids on epigenetic mechanisms that affect the development of chronic diseases or induce protective effects on metabolic alterations. METHODS:A targeted search was conducted in the PubMed/Medline databases using the keywords "fatty acids and epigenetic". The data were analy

SUBMITTER: Gonzalez-Becerra K 

PROVIDER: S-EPMC6792183 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature