Signatures of selection for resistance to Haemonchus contortus in sheep and goats.

ABSTRACT: BACKGROUND:Gastrointestinal nematode infection (GNI) is the most important disease affecting the small ruminant industry in U.S. The environmental conditions in the southern United States are ideal for the survival of the most pathogenic gastrointestinal nematode, Haemonchus contortus. Host genetic variation for resistance to H. contortus allows selective breeding for increased resistance of animals. This selection process increases the prevalence of particular alleles in sheep and goats and creates unique genetic patterns in the genome of these species. The aim of this study was to identify loci with divergent allelic frequencies in a candidate gene panel of 100 genes using two different approaches (frequentist and Bayesian) to estimate Fst outliers in three different breeds of sheep and

SUBMITTER: Estrada-Reyes ZM 

PROVIDER: S-EPMC6792194 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature