CEPICS: A Comparison and Evaluation Platform for Integration Methods in Cancer Subtyping.

ABSTRACT: Cancer subtypes can improve our understanding of cancer, and suggest more precise treatment for patients. Multi-omics molecular data can characterize cancers at different levels. Up to now, many computational methods that integrate multi-omics data for cancer subtyping have been proposed. However, there are no consistent criteria to evaluate the integration methods due to the lack of gold standards (e.g., the number of subtypes in a specific cancer). Since comprehensive evaluation and comparison between different methods serves as a useful tool or guideline for users to select an optimal method for their own purpose, we develop a scalable platform, CEPICS, for comprehensively evaluating and comparing multi-omics data integration methods in cancer subtyping. Given a user-specified maximum n

SUBMITTER: Duan R 

PROVIDER: S-EPMC6792302 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature