Tap Water Contributions to Plasma Concentrations of Poly- and Perfluoroalkyl Substances (PFAS) in a Nationwide Prospective Cohort of U.S. Women.

ABSTRACT:

Background

Between 2013 and 2015, concentrations of poly- and perfluoroalkyl substances (PFAS) in public drinking water supplies serving at least six million individuals exceeded the level set forth in the health advisory established by the U.S. Environmental Protection Agency. Other than data reported for contaminated sites, no systematic or prospective data exist on the relative source contribution (RSC) of drinking water to human PFAS exposures.

Objectives

This study estimates the RSC of tap water to overall PFAS exposure among members of the general U.S.

Population

Methods

We measured concentrations of 15 PFAS in home tap water samples collected in 1989-1990 from 225 participants in a nationwide prospective cohort of U.S. women: the Nurses' Health Study (N

SUBMITTER: Hu XC 

PROVIDER: S-EPMC6792361 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature