Lymph node ratio as valuable predictor in pancreatic cancer treated with R0 resection and adjuvant treatment.

ABSTRACT:

Background

Lymph-node (LN) metastasis is an important prognostic factor in resected pancreatic cancer. In this study, the prognostic value of American Joint Committee on Cancer (AJCC) 8th edition N stage, lymph-node ratio (LNR), and log odds of positive lymph nodes (LODDS) in resected pancreatic cancer was investigated.

Methods

Between January 2005 and December 2017, there were 351 patients with pancreatic cancer treated with R0 resection and adjuvant therapy at Seoul National University Hospital. Relationships between the three LN parameters and overall survival (OS) and recurrence-free survival (RFS) were evaluated using a log-rank test and Cox proportional hazard regression model. Each multivariate-adjusted LN parameter was internally validated by bootstrap-corrected Harr

SUBMITTER: You MS 

PROVIDER: S-EPMC6794802 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature