Robust structure measures of metabolic networks that predict prokaryotic optimal growth temperature.

ABSTRACT:

Background

Metabolic networks reflect the relationships between metabolites (biomolecules) and the enzymes (proteins), and are of particular interest since they describe all chemical reactions of an organism. The metabolic networks are constructed from the genome sequence of an organism, and the graphs can be used to study fluxes through the reactions, or to relate the graph structure to environmental characteristics and phenotypes. About ten years ago, Takemoto et al. (2007) stated that the structure of prokaryotic metabolic networks represented as undirected graphs, is correlated to their living environment. Although metabolic networks are naturally directed graphs, they are still usually analysed as undirected graphs.

Results

We implemented a pipeline to reconstruct metab

SUBMITTER: Weber Zendrera A 

PROVIDER: S-EPMC6794987 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature