Real-world data in retinal diseases treated with anti-vascular endothelial growth factor (anti-VEGF) therapy - a systematic approach to identify and characterize data sources.

ABSTRACT: BACKGROUND:Real-world data (RWD) has been a valuable addition to the scientific literature regarding treatment pathways, clinical outcomes and characteristics of patients with retinal diseases in recent years. Registries, observational studies and patient databases are often used for real-world research. However, there is limited information for each data source on the design, consistency, data captured, limitations and usability for assessing research questions. Using a systematic approach, we identified RWD sources for patients with retinal diseases and assessed them for completeness of data relating to different outcomes. METHODS:A systematic literature review was carried out to identify RWD sources for patients with retinal disease. Potentially relevant articles published between 2006

SUBMITTER: Daien V 

PROVIDER: S-EPMC6796465 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature