The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population.

ABSTRACT:

Background

The risk of obesity is determined by complex interactions between genetic and environmental factors. Little research to date has investigated the interaction between gene and food intake. The aim of the current study is to explore the potential effect of fat mass and obesity-associated protein gene (FTO) rs9939609 and rs9930506 single nucleotide polymorphism (SNP) on the pattern of food intake in the Emirati population.

Methods

Adult healthy Emirati subjects with Body mass index (BMI) of 16-40 kg/m2 were included in the study. Genotyping for FTO rs9939609(A>T) and rs9930506(A>G) was performed using DNA from saliva samples. Subjects were categorized according to the WHO classification by calculating the BMI to compare different classes. Dietary intake was assessed

SUBMITTER: Saber-Ayad M 

PROVIDER: S-EPMC6797190 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature