Efficacy and neural mechanism of acupuncture treatment in older adults with subjective cognitive decline: study protocol for a randomised controlled clinical trial.

ABSTRACT:

Introduction

Subjective cognitive decline (SCD) refers to individuals' perceived decline in memory and/or other cognitive abilities relative to their previous level of performance, while objective neuropsychological deficits are not observed. SCD may represent a preclinical phase of Alzheimer's disease. At this very early stage of decline, intervention could slow the rate of incipient decline to prolong and preserve cognitive and functional abilities. However, there is no effective treatment recommended for individuals with SCD. Acupuncture, as a non-pharmacological intervention, has been widely employed for patients with cognitive disorders.

Methods and analysis

The proposed study is a randomised, assessor-blinded and placebo-controlled study that investigates the efficacy

SUBMITTER: Yan CQ 

PROVIDER: S-EPMC6797373 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature