Hybrid Polyester-Hydrogel Electrospun Scaffolds for Tissue Engineering Applications.

ABSTRACT: Electrospinning is an attractive fabrication process providing a cost-effective and straightforward technic to make extra-cellular matrix (ECM) mimicking scaffolds that can be used to replace or repair injured tissues and organs. Synthetic polymers as poly (ε-caprolactone) (PCL) and poly (ethylene oxide terephthalate)-poly(butylene terephthalate) (PEOT/PBT) have been often used to produce scaffolds due to their good processability, mechanical properties, and suitable biocompatibility. While synthetic polymers can mimic the physical features of native ECM, natural polymers like alginate are better suited to recapitulate its hydrated state or introduce functional groups that are recognized by cells (e.g., -NH2). Thus, this study aims at creating electrospun meshes made of blended synthetic a

SUBMITTER: Goncalves de Pinho AR 

PROVIDER: S-EPMC6798037 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature