Early prognostication of neurological outcome by heart rate variability in adult patients with out-of-hospital sudden cardiac arrest.

ABSTRACT: BACKGROUND:Most deaths of comatose survivors of out-of-hospital sudden cardiac arrest result from withdrawal of life-sustaining treatment (WLST) decisions based on poor neurological prognostication and the family's intention. Thus, accurate prognostication is crucial to avoid premature WLST decisions. However, targeted temperature management (TTM) with sedation or neuromuscular blockade against shivering significantly affects early prognostication. In this study, we investigated whether heart rate variability (HRV) analysis could prognosticate poor neurological outcome in comatose patients undergoing hypothermic TTM. METHODS:Between January 2015 and December 2017, adult patients with out-of-hospital sudden cardiac arrest, successfully resuscitated in the emergency department and admitted t

SUBMITTER: Endoh H 

PROVIDER: S-EPMC6798365 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature