Surgical outcomes in adults with purpura fulminans: a systematic review and patient-level meta-synthesis.

ABSTRACT:

Background

Cutaneous manifestations of purpura fulminans (PF) present many challenges for clinicians and surgeons. In a state of septic shock complicated by limb ischemia, surgical interventions are necessary to control the pathological cascade and improve patient outcomes. The objective of this article was to report etiologies and surgical outcomes associated with cutaneous manifestations in adults.

Methods

This systematic review and meta-analysis compared 190 adult patients with etiologies, signs and symptoms, and surgical outcomes associated with cutaneous manifestations of PF. The PubMed, EMBASE, Cochrane Library, Web of Science, and Scopus databases were systematically and independently searched. Patient and clinical characteristics, surgical interventions, outcomes, an

SUBMITTER: Klifto KM 

PROVIDER: S-EPMC6798408 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature