Cognitive functioning in patients with classical galactosemia: a systematic review.

ABSTRACT:

Background

Patients with the metabolic disorder classical galactosemia suffer from long-term complications despite a galactose-restricted diet, including a below average intelligence level. The aim of the current review was to investigate the incidence and profile of cognitive impairments in patients with classical galactosemia.

Method

MEDLINE, EMBASE and PsychINFO were searched up to 23 October 2018 for studies examining information processing speed, attention, memory, language, visuospatial functioning, executive functioning and social cognition in patients with confirmed classical galactosemia utilizing standardized neuropsychological tests. Data synthesis followed a narrative approach, since the planned meta-analysis was not possible due to large variability between the

SUBMITTER: Hermans ME 

PROVIDER: S-EPMC6798502 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature