Factors Affecting Detection Power of Blood Oxygen-Level Dependent Signal in Resting-State Functional Magnetic Resonance Imaging Using High-Resolution Echo-Planar Imaging.

ABSTRACT: Latest developments in magnetic resonance imaging (MRI) hardware and software have significantly improved image acquisition for functional MRI (fMRI) techniques, including resting-state fMRI (rsfMRI). Specifically, with improvements in gradient and radiofrequency coils and advances in pulse sequence designs, functional images with higher spatiotemporal resolution can be achieved. However, while smaller voxel size has the benefit of resolving finer brain structures, it also decreases voxel-wise signal-to-noise ratio (SNR) and, subsequently, temporal SNR (tSNR), which is critical for the sensitivity of fMRI. Although the improved temporal resolution allows more image frames to be collected per unit time, the ability to detect brain activity by using the high spatiotemporal fMRI has not been

SUBMITTER: Caparelli EC 

PROVIDER: S-EPMC6798806 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature