Hybrid superhydrophilic-superhydrophobic micro/nanostructures fabricated by femtosecond laser-induced forward transfer for sub-femtomolar Raman detection.

ABSTRACT: Raman spectroscopy plays a crucial role in biochemical analysis. Recently, superhydrophobic surface-enhanced Raman scattering (SERS) substrates have enhanced detection limits by concentrating target molecules into small areas. However, due to the wet transition phenomenon, further reduction of the droplet contact area is prevented, and the detection limit is restricted. This paper proposes a simple method involving femtosecond laser-induced forward transfer for preparing a hybrid superhydrophilic-superhydrophobic SERS (HS-SERS) substrate by introducing a superhydrophilic pattern to promote the target molecules to concentrate on it for ultratrace detection. Furthermore, the HS-SERS substrate is heated to promote a smaller concentrated area. The water vapor film formed by the contact of the

SUBMITTER: Ma X 

PROVIDER: S-EPMC6799889 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature