Impacts of an opioid overdose prevention intervention delivered subsequent to acute care.

ABSTRACT:

Background

Opioid overdose is a major and increasing cause of injury and death. There is an urgent need for interventions to reduce overdose events among high-risk persons.

Methods

Adults at elevated risk for opioid overdose involving heroin or pharmaceutical opioids who had been cared for in an emergency department (ED) were randomised to overdose education combined with a brief behavioural intervention and take-home naloxone or usual care. Outcomes included: (1) time to first opioid overdose-related event resulting in medical attention or death using competing risks survival analysis; and (2) ED visit and hospitalisation rates, using negative binomial regression and adjusting for time at risk.

Results

During the follow-up period, 24% of the 241 participants had at l

SUBMITTER: Banta-Green CJ 

PROVIDER: S-EPMC6800078 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature