Universal Testing, Expanded Treatment, and Incidence of HIV Infection in Botswana.

ABSTRACT:

Background

The feasibility of reducing the population-level incidence of human immunodeficiency virus (HIV) infection by increasing community coverage of antiretroviral therapy (ART) and male circumcision is unknown.

Methods

We conducted a pair-matched, community-randomized trial in 30 rural or periurban communities in Botswana from 2013 to 2018. Participants in 15 villages in the intervention group received HIV testing and counseling, linkage to care, ART (started at a higher CD4 count than in standard care), and increased access to male circumcision services. The standard-care group also consisted of 15 villages. Universal ART became available in both groups in mid-2016. We enrolled a random sample of participants from approximately 20% of households in each community and

SUBMITTER: Makhema J 

PROVIDER: S-EPMC6800102 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature