Measurement of birth outcomes in analyses of the impact of maternal influenza vaccination.

ABSTRACT:

Background

The estimated association of maternal influenza vaccination and birth outcomes may be sensitive to methods used to define preterm birth or small-for-gestational age (SGA).

Methods

In a cohort of pregnant women in Lao People's Democratic Republic, we estimated gestational age from: (a) date of last menstrual period (LMP), (b) any prenatal ultrasound, (c) first trimester ultrasound, (d) Ballard Score at delivery, and (e) an algorithm combining LMP and ultrasound. Infants were classified as SGA at birth using a Canadian, global, and equation-based growth reference. We estimated the association of maternal influenza vaccination and birth outcomes, by influenza activity, using multivariable log-binomial regression and Cox proportional hazards regression with vaccinatio

SUBMITTER: Rolfes MA 

PROVIDER: S-EPMC6800304 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature