Phylogenetic characterization of rhinoviruses from infants in Sarlahi, Nepal.

ABSTRACT:

Problem

Rhinoviruses (RVs), the most common causes of acute respiratory infections in young children and infants, are highly diverse genetically.

Objective

To characterize the RV types detected with respiratory illness episodes in infants in Nepal.

Study methods

Infants born to women enrolled in a randomized trial of maternal influenza immunization in rural, southern Nepal were followed with household-based weekly surveillance until 180 days of age. Infants with respiratory symptoms had nasal swabs tested for twelve respiratory viruses. A subset with RV alone was selected for sequencing of the VP4/2 gene to identify RV types.

Results

Among 547 RV-only positive illnesses detected from December 2012 to April 2014, 285 samples (52%) were sequenced. RV-A, B, and C

SUBMITTER: Kuypers J 

PROVIDER: S-EPMC6800797 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature