Do Culture Negative Periprosthetic Joint Infections Remain Culture Negative?

ABSTRACT:

Background

Diagnosis and treatment of culture negative total knee arthroplasty (TKA) periprosthetic joint infection (PJI) is challenging. There is debate over whether culture negative PJI confers increased risk of failure and which organisms are responsible. It is also unclear as to what factors predict conversion from culture negative to culture positivity. To address these issues, we performed an observational study to detect factors associated with transition from culture negative to culture positive TKA PJI in those patients that failed irrigation and debridement (I&D), determine the incidence of this transition, and identify those organisms that were associated with treatment failure.

Methods

A multicenter observational cohort study was performed on patients with TKA PJ

SUBMITTER: Hersh BL 

PROVIDER: S-EPMC6801070 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature