Phage-centric ecological interactions in aquatic ecosystems revealed through ultra-deep metagenomics.

ABSTRACT: The persistent inertia in the ability to culture environmentally abundant microbes from aquatic ecosystems represents an obstacle in disentangling the complex web of ecological interactions spun by a diverse assortment of participants (pro- and eukaryotes and their viruses). In aquatic microbial communities, the numerically most abundant actors, the viruses, remain the most elusive, and especially in freshwaters their identities and ecology remain unknown. Here, using ultra-deep metagenomic sequencing from pelagic freshwater habitats, we recovered complete genomes of > 2000 phages, including small "miniphages" and large "megaphages" infecting iconic freshwater prokaryotic lineages. For instance, abundant freshwater Actinobacteria support infection by a very broad size range of phages (13-2

SUBMITTER: Kavagutti VS 

PROVIDER: S-EPMC6802176 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature