Midlife physical activity is associated with lower incidence of vascular dementia but not Alzheimer's disease.

ABSTRACT: BACKGROUND:Physical activity might reduce the risk of developing dementia. However, it is still unclear whether the protective effect differs depending on the subtype of dementia. We aimed to investigate if midlife physical activity affects the development of vascular dementia (VaD) and Alzheimer's disease (AD) differently in two large study populations with different designs. METHODS:Using a prospective observational design, we studied whether long-distance skiers of the Swedish Vasaloppet (n = 197,685) exhibited reduced incidence of VaD or AD compared to matched individuals from the general population (n = 197,684) during 21 years of follow-up (median 10, interquartile range (IQR) 5-15 years). Next, we studied the association between self-reported physical activity, stated twice 5 years

SUBMITTER: Hansson O 

PROVIDER: S-EPMC6802179 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature