Association of Estimated Pulse Wave Velocity With Survival: A Secondary Analysis of SPRINT.

ABSTRACT:

Importance

Aortic stiffness, as assessed by carotid-femoral pulse wave velocity, is an independent predictor of future events in individuals with hypertension. Recent data suggest a predictive role of estimated pulse wave velocity (ePWV) calculated by previously published equations using age and blood pressure in future events in individuals with hypertension.

Objective

To investigate whether ePWV and its response to treatment predict survival in the Systolic Blood Pressure Intervention Trial (SPRINT).

Design, setting, and participants

This exploratory, hypothesis-generating, post hoc secondary analysis conducted from October 1, 2018, to August 31, 2019, examined data from 9361 participants in SPRINT and calculated ePWV at baseline and at 12 months. Adjusted hazard ra

SUBMITTER: Vlachopoulos C 

PROVIDER: S-EPMC6802234 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature