Efficacy and Safety of Varenicline for Adolescent Smoking Cessation: A Randomized Clinical Trial.

ABSTRACT:

Importance

Cigarette smoking is the leading cause of preventable morbidity and mortality in the United States and worldwide, and most tobacco users begin smoking in adolescence. Although advances have yielded efficacious pharmacotherapies to complement smoking cessation counseling in adults, far less progress has been made in addressing tobacco use in adolescence.

Objective

To evaluate the efficacy and safety of varenicline tartrate for smoking cessation in adolescents and young adults.

Design, setting, and participants

This 2-group randomized, placebo-controlled, double-blind intention-to-treat clinical trial enrolled a volunteer sample of treatment-seeking adolescent and young adult cigarette smokers (n = 157) aged 14 to 21 years at an outpatient clinical site in Ch

SUBMITTER: Gray KM 

PROVIDER: S-EPMC6802269 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature