Long-term Outcomes of Lung Transplant With Ex Vivo Lung Perfusion.

ABSTRACT:

Importance

The mortality rate for individuals on the wait list for lung transplant is 15% to 25%, and still only 20% of lungs from multiorgan donors are used for lung transplant. The lung donor pool may be increased by assessing and reconditioning high-risk extended criteria donor lungs with ex vivo lung perfusion (EVLP), with similar short-term outcomes.

Objective

To assess the long-term outcomes of transplant recipients of donor lungs treated with EVLP.

Design, setting, and participants

This retrospective cohort single-center study was conducted from August 1, 2008, to February 28, 2017, among 706 recipients of donor lungs not undergoing EVLP and 230 recipients of donor lungs undergoing EVLP.

Exposure

Donor lungs undergoing EVLP.

Main outcomes and measures

SUBMITTER: Divithotawela C 

PROVIDER: S-EPMC6802423 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature