Correlation between Quality and Geographical Origins of CortexPeriplocae, Based on the Qualitative and Quantitative Determination of Chemical Markers Combined with Chemical Pattern Recognition.

ABSTRACT: Quality assessment of Cortex Periplocae remains a challenge, due to its complex chemical profile. This study aims to investigate the chemical components of Cortex Periplocae, including its non-volatile and volatile constituents, via liquid chromatograph-mass spectrometry (LC-MS/MS) and gas chromatography-mass spectrometry (GC-MS) assays. The established strategy manifested that Cortex Periplocae from different producing areas was determined by identifying 27 chemical markers with ultra-high-performance liquid chromatography, coupled with quadrupole tandem time-of-flight mass spectrometry (UPLC-Q-TOF-MS/MS), including four main groups of cardiac glycosides, organic acids, aldehydes, and oligosaccharides. These groups' variable importance in the projection (VIP) were greater than 1. Simultan

SUBMITTER: Gao M 

PROVIDER: S-EPMC6804018 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature