Association of Neurocognitive and Physical Function With Gait Speed in Midlife.

ABSTRACT:

Importance

Gait speed is a well-known indicator of risk of functional decline and mortality in older adults, but little is known about the factors associated with gait speed earlier in life.

Objectives

To test the hypothesis that slow gait speed reflects accelerated biological aging at midlife, as well as poor neurocognitive functioning in childhood and cognitive decline from childhood to midlife.

Design, setting, and participants

This cohort study uses data from the Dunedin Multidisciplinary Health and Development Study, a population-based study of a representative 1972 to 1973 birth cohort in New Zealand that observed participants to age 45 years (until April 2019). Data analysis was performed from April to June 2019.

Exposures

Childhood neurocognitive functi

SUBMITTER: Rasmussen LJH 

PROVIDER: S-EPMC6804027 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature