Characterization of Eight Novel Spiroleptosphols from Fusarium avenaceum.

ABSTRACT: Chemical analyses of Fusarium avenaceum grown on banana medium resulted in eight novel spiroleptosphols, T1, T2 and U-Z (1-8). The structures were elucidated by a combination of high-resolution mass spectrometric data and 1- and 2-D NMR experiments. The relative stereochemistry was assigned by 1H coupling and NOESY/ROESY experiments. Absolute stereochemistry established for 7 by vibrational circular dichroism was found analogous to that of the putative polyketide spiroleptosphol from Leptosphaeria doliolum.

SUBMITTER: Westphal KR 

PROVIDER: S-EPMC6804164 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature