Analysis of ancient mtDNA from the medieval archeological site of Amiternum (L'Aquila), central Italy.

ABSTRACT: Study of ancient DNA makes it possible to analyze genetic relationships between individuals and populations of past and present. In this paper we have analyzed remains of human bones, dating back to the 8th-10th century AD, from the burials found in the Cathedral of Santa Maria in Civitate, archaeological site of Amiternum, L'Aquila, Italy. As a genetic marker, the hypervariable region 1 of mitochondrial DNA (HVR1) was selected. To obtain reliable sequences from the hypervariable region 1 of mtDNA (HVR1) were performed: multiple extractions, template quantification and cloning of PCR products. The sequences obtained were compared with Anderson's sequence for the identification of polymorphisms (SNP) and haplogroups. The data obtained were analyzed with various software and ph

SUBMITTER: Poma A 

PROVIDER: S-EPMC6804371 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature