Identifying organs at risk for radiation-induced late dysphagia in head and neck cancer patients.

ABSTRACT:

Background and purpose

Dysphagia is a common, severe and dose-limiting toxicity after oncological treatment of head and neck cancer (HNC). This study aims to investigate relationships between radiation doses to structures involved in normal swallowing and patient-reported as well as clinically measured swallowing function in HNC patients after curative (chemo-) radiation therapy (RT) with focus on late effects.

Materials and methods

Patients (n = 90) with HNC curatively treated with RT ± chemotherapy in 2007-2015 were assessed for dysphagia post-treatment by telephone interview and videofluoroscopy (VFS). A study-specific symptom score was used to determine patient-reported dysphagia. The Penetration-Aspiration Scale (PAS) was applied to determine swallowing function by VFS

SUBMITTER: Hedstrom J 

PROVIDER: S-EPMC6804434 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature