Estimating incidence rates of grouped HPV types: A systematic review and comparison of the impact of different epidemiological assumptions.

ABSTRACT:

Background

Some studies on human papillomavirus (HPV) provide not only type-specific incidence rates (IR), but also IRs of HPV groupings (e.g. the nonavalent grouping). We made an inventory of the different approaches used to calculate such IRs and assessed their impact on the estimated IRs of HPV groupings.

Methods

We performed a systematic review assessing all approaches used in literature to estimate IRs. Subsequently we applied these approaches to data of a Dutch cohort study on HPV in men who have sex with men (H2M). IRs were estimated for six different HPV groupings.

Results

The systematic review yielded six different approaches (A-F) for estimating the IRs, varying in exclusion criteria at baseline, and the definitions of an incident event and person-time. Appl

SUBMITTER: Jongen VW 

PROVIDER: S-EPMC6804437 | biostudies-literature | 2019 Dec

REPOSITORIES: biostudies-literature