Sarcopenia as a prognostic factor for survival in patients with locally advanced gastroesophageal adenocarcinoma.

ABSTRACT: BACKGROUND AND AIMS:Patients with gastric cancer often show signs of malnutrition. We sought to evaluate the influence of sarcopenia in patients with locally advanced, not metastasized, gastric or gastro-esophageal junction (GEJ) cancer undergoing curative treatment (perioperative chemotherapy and surgery) on morbidity and mortality in order to identify patients in need for nutritional intervention. PATIENTS AND METHODS:Two-centre study, conducted in the Frankfurt University Clinic and Krankenhaus Nordwest (Frankfurt) as part of the University Cancer Center Frankfurt (UCT). 47/83 patients were treated in the FLOT trial (NCT01216644). Patients´ charts were reviewed for clinical data. Two consecutive CT scans were retrospectively analyzed to determine the degree of sarcopenia. Survival was c

SUBMITTER: Koch C 

PROVIDER: S-EPMC6805048 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature