Management and outcomes of pneumothorax in adult patients with Langerhans cell Histiocytosis.

ABSTRACT: BACKGROUND:Pneumothorax may recur during pulmonary Langerhans cell histiocytosis (PLCH) patients' follow-up and its management is not standardised. The factors associated with pneumothorax recurrence are unknown. METHODS:In this retrospective study, PLCH patients who experienced a pneumothorax and were followed for at least 6 months after the first episode were eligible. The objectives were to describe the treatment of the initial episode and pneumothorax recurrences during follow-up. We also searched for factors associated with pneumothorax recurrence and evaluated the effect on lung function outcome. Time to recurrence was estimated by the Kaplan Meier method and the cumulative hazard of recurrence handling all recurrent events was estimated. Univariate Cox models and Andersen-Gill count

SUBMITTER: Le Guen P 

PROVIDER: S-EPMC6805357 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature