Paving the way for more precise diagnosis of EcPV2-associated equine penile lesions.

ABSTRACT: BACKGROUND:There is growing evidence that equine papillomavirus type 2 (EcPV2) infection is causally associated with the development of equine genital squamous cell carcinomas (SCCs). Early stages of disease present clinically as plaques or wart-like lesions which can gradually progress to tumoural lesions. Histologically these lesions are inconsistently described as benign hyperplasia, papilloma, penile intraepithelial neoplasia (PIN), carcinoma in situ (CIS) or SCC. Guidelines for histological classification of early SCC precursor lesions are not precisely defined, leading to potential misdiagnosis. The aim of this study was to identify histologic criteria and diagnostic markers allowing for a more accurate diagnosis of EcPV2-associated equine penile lesions. RESULTS:A total of 61 archiv

SUBMITTER: Ramsauer AS 

PROVIDER: S-EPMC6805557 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature