Aortic valve calcification volumes and chronic brain infarctions in patients undergoing transcatheter aortic valve implantation.

ABSTRACT: Chronic silent brain infarctions, detected as new white matter hyperintensities on magnetic resonance imaging (MRI) following transcatheter aortic valve implantation (TAVI), are associated with long-term cognitive deterioration. This is the first study to investigate to which extent the calcification volume of the native aortic valve (AV) measured with cardiac computed tomography angiography (CTA) predicts the increase in chronic white matter hyperintensity volume after TAVI. A total of 36 patients (79 ± 5 years, median EuroSCORE II 1.9%, Q₁-Q₃ 1.5-3.4%) with severe AV stenosis underwent fluid attenuation inversion recovery (FLAIR) MRI < 24 h prior to TAVI and at 3 months follow-up for assessment of cerebral white matter hyperintensity volume (mL). Calcification volum

SUBMITTER: Vlastra W 

PROVIDER: S-EPMC6805808 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature