Healthy Lifestyle and Cardiac Vagal Modulation Over 10 Years: Whitehall II Cohort Study.

ABSTRACT: Background Increased vagal modulation is a mechanism that may partially explain the protective effect of healthy lifestyles. However, it is unclear how healthy lifestyles relate to vagal regulation longitudinally. We prospectively examined associations between a comprehensive measure of 4 important lifestyle factors and vagal modulation, indexed by heart rate variability (HRV) over 10 years. Methods and Results The fifth (1997-1999), seventh (2002-2004), and ninth (2007-2009) phases of the UK Whitehall II cohort were analyzed. Analytical samples ranged from 2059 to 3333 (mean age: 55.7 years). A healthy lifestyle score was derived by giving participants 1 point for each healthy factor: physically active, not smoking, moderate alcohol consumption, and healthy body mass index. Two vagally me

SUBMITTER: Jandackova VK 

PROVIDER: S-EPMC6806037 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature