Association of Exposure to Ambient Air Pollution With Thyroid Function During Pregnancy.

ABSTRACT: Importance:Air pollutants interact with estrogen nuclear receptors, but their effect on thyroid signaling is less clear. Thyroid function is of particular importance for pregnant women because of the thyroid's role in fetal brain development. Objective:To determine the short-term association of exposure to air pollution in the first trimester with thyroid function throughout pregnancy. Design, Setting, and Participants:In this cohort study, 9931 pregnant women from 4 European cohorts (the Amsterdam Born Children and Their Development Study, the Generation R Study, Infancia y Medio Ambiente, and Rhea) and 1 US cohort (Project Viva) with data on air pollution exposure and thyroid function during pregnancy were included. The recruitment period for the Amsterdam Born Children and Their Develop

SUBMITTER: Ghassabian A 

PROVIDER: S-EPMC6806433 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature