Global patterns and trends in ovarian cancer incidence: age, period and birth cohort analysis.

ABSTRACT:

Background

Ovarian cancer (OC) is the seventh most common malignancy worldwide and the most lethal gynaecological malignancy. We aimed to explore global geographical patterns and temporal trends from 1973 to 2015 for 41 countries in OC incidence and especially to analyse the birth cohort effect to gain further insight into the underlying causal factors of OC and identify countries with increasing risk of OC.

Methods

OC data were drawn from the Cancer Incidence in Five Continents databases and online databases published by governments. The joinpoint regression model was applied to detect changes in OC trends. The age-period-cohort model was applied to explore age and birth cohort effects.

Results

The age-standardized rate of OC incidence ranged from 3.0 to 11.4 per 100

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC6806513 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature