The Syndrome of Inappropriate Secretion of AntiDiuretic Hormone in Patients With Brucellosis.

ABSTRACT:

Objective

Various studies have shown that a number of infectious disease causes syndrome of inappropriate antidiuretic hormone (SIADH). However, the relationship between infectious disease and SIADH is not yet fully known. In this prospective study, we aimed to assess the presence of SIADH in patients with brucellosis.

Patients and methods

Thirty-five patients with acute brucellosis were retrospectively reviewed. The diagnosis of brucellosis was performed using the Wright test in connection with blood culture. SIADH was defined by euvolemic hyponatremia (serum sodium level lower than 135 mEq/l) with increased urinary sodium excretion (urinary sodium higher than 40 mmol/l).

Results

Of the 35 patients, 19 (54%) had SIADH; 20 (57%) also had hypouricemia (uric acid level

SUBMITTER: Dulger AC 

PROVIDER: S-EPMC6806686 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature