Influence of Body Mass Index on the Activated Clotting Time Under Weight-Based Heparin Dose.

ABSTRACT:

Background

Activated clotting time (ACT) has been successfully applied during percutaneous coronary intervention (PCI) to monitor the extent of thrombin inhibition and anti-coagulation from unfractionated heparin (UFH) aiming to reduce the incidence of thrombotic adverse events and hemorrhagic complications. And this investigation was to explore the influence of body mass index (BMI) on ACT in patients received weight-based dose of UFH during PCI treatment.

Methods

78 male patients undergoing coronary angiography or PCI treatment with a mean age of 63.86 ± 6.89 years were enrolled in this study. The patients were statistically divided into four quartiles according to their BMI. The ACT values were recorded as ACT0 , ACT5 , ACT10 , ACT30 and ACT60 , respectively. Taking the p

SUBMITTER: Hong X 

PROVIDER: S-EPMC6807074 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature