Antifungal Activity of Propolis Against Yeasts Isolated From Blood Culture: In Vitro Evaluation.

ABSTRACT:

Background

Due to the failure of available antifungal agents in the treatment of candidemia and the toxic activities of these drugs, a lot of researches are being conducted to develop new nontoxic and effective antifungal agents for optimal control of fungal pathogens. The aim of this study is to evaluate the in vitro antifungal activity of propolis against yeasts isolated from the blood cultures of intensive care unit patients.

Methods

Seventy-six strains were included in this study. The in vitro antifungal activity of propolis, fluconazole (FLU), and itraconazole (ITR) was investigated by the microdilution broth methods (CLSI guidelines M27-A3 for yeast). The propolis sample was collected from Kayseri, Turkey.

Results

Of the 76 isolates, 33 were identified as Candid

SUBMITTER: Mutlu Sariguzel F 

PROVIDER: S-EPMC6807121 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature