MetaDEGalaxy: Galaxy workflow for differential abundance analysis of 16s metagenomic data.

ABSTRACT: Metagenomic sequencing is an increasingly common tool in environmental and biomedical sciences.  While software for detailing the composition of microbial communities using 16S rRNA marker genes is relatively mature, increasingly researchers are interested in identifying changes exhibited within microbial communities under differing environmental conditions. In order to gain maximum value from metagenomic sequence data we must improve the existing analysis environment by providing accessible and scalable computational workflows able to generate reproducible results. Here we describe a complete end-to-end open-source metagenomics workflow running within Galaxy for 16S differential abundance analysis. The workflow accepts 454 or Illumina sequence data (either overlapping or non-overlapping p

SUBMITTER: Thang MWC 

PROVIDER: S-EPMC6807170 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature