Using Novel Method to Detect Different Cancer-Cell Stages of Model Human Lung Carcinoma.

ABSTRACT:

Background

Synchrotron radiation infrared (SR-IR) microspectroscopy and SR-IR spectroscopic imaging are extremely valuable techniques for determining the molecular composition of biological and biomedical samples. In this work, SR-IR is applied in the study of the lung cancer cells in different cell cycles.

Methods

We use a novel synchrotron based radiation infrared system combined synchronized model human lung carcinoma to reveal its unique character pattern.

Results

After using SR-IR microspectroscopy, we discovered that the ratio of protein to lipid in G1 and G2 states is around 4.0 and 6.1, respectively. Moreover, for the DNA at the wavenumber position of 1225 cm(-1) , the intensity ratio of G2 state to G1 state is approximately 1.6. These data indicate that the c

SUBMITTER: Cheng HY 

PROVIDER: S-EPMC6807252 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature