Specialization of small non-conjugative plasmids in Escherichia coli according to their family types.

ABSTRACT: We undertook a comprehensive comparative analysis of a collection of 30 small (<25 kb) non-conjugative Escherichia coli plasmids previously classified by the gene sharing approach into 10 families, as well as plasmids found in the National Center for Biotechnology Information (NCBI) nucleotide database sharing similar genomic sequences. In total, 302 mobilizable (belonging to 2 MOB_rep and 5 MOB_RNA families) and 106 non-transferable/relaxase-negative (belonging to three ReL_RNA families) plasmids were explored. The most striking feature was the specialization of the plasmid family types that was not related to their transmission mode and replication system. We observed a range of host strain specificity, from narrow E. coli host specificity to b

SUBMITTER: Branger C 

PROVIDER: S-EPMC6807383 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature