Circulating miRNAs, Small but Promising Biomarkers for Autism Spectrum Disorder.

ABSTRACT: Autism spectrum disorder (ASD) refers to a heterogeneous group of complex neurodevelopmental disorders characterized by social skill and communication deficits, along with stereotyped repetitive behavior. miRNAs, small non-coding RNAs that have been recognized as critical regulators of gene expression, play a key role in the neurodevelopmental transcriptional networks of the human brain. Previous investigations have proven that circulating miRNAs open up new possibilities for the emerging roles of diagnostic and prognostic biomarkers in human disorders and diseases. Biomarker development has been progressively becoming more recognized as a cornerstone in medical diagnosis, paving the way to drug discoveries and limiting the progression of various diseases. Due to the complexity of ASD, con

SUBMITTER: Salloum-Asfar S 

PROVIDER: S-EPMC6808050 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature